Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 4th International Conference on Polymer Chemistry Stockholm, Sweden.

Day 1 :

Keynote Forum

Bernabe L. Rivas

University of Concepcion, Chile

Keynote: Functional polymers to remove inorganic contaminants

Time : 9.35-10.20

Conference Series Euro Polymer Chemistry 2018 International Conference Keynote Speaker Bernabe L. Rivas photo
Biography:

Bernabe L. Rivas has completed his PhD at the University of Concepcion (1980) and postdoctoral studies from Tuebingen University, Germany with Humboldt Foundation Fellows (1989-1991). He is the Vice Rector of the University of Concepción. Leader of the research group about Synthesis and Applications of -Functional Polymers, Polyelectrolytes, Resins with Retention Properties for Pollutants Ions.–Polychelatogens in combination with ultrafiltration membranes. Polymer-metal complexes as biocides. Nanocomposites from polypropylene and biopolymers. He has published more than 400 papers in reputed journals, 29 chapter of books, h factor 34, and has been serving as an editorial board member of journals.

 

Abstract:

The major percentage of inorganic compounds found in groundwater is coming from natural origins. However, significant amounts are also a result of the human activities. Thus, the removal/remediation of these substances is necessary. Over the last few years, discarding solid and/or liquid waste products containing heavy metals emanating from industrial processes has received much attention.

Membrane filtration easily allows this separation by means of the method known as the liquid-phase polymer-based retention (LPR) technique. Applications of water-soluble polymers to the homogeneous enrichment or selective separation of various metal ions from dilute solutions have been reported[1].  Through to washing or enrichment methods, Cr(VI), V(V), Mo(VI), and As(V) removal experiments were carried out at different pH using water-soluble cationic polymers (WSCPs) containing quaternary ammonium salts. The results showed highest retention capacity of oxyanions depending on the pH.

Polymer-clay nanocomposites researches have presented a great attention from scientific community because nanocomposites materials present enhanced properties (mechanical, thermal, and barrier properties) compared with starting material (unloaded polymers). Diverse clay materials have been used as filler in nanocomposites; montmorillonite, kaolinite, vermiculite, among others. The use of polymer matrix with organic functional with capability to retain ion and filler such as clays lead to nanocomposite ion exchange resins. We have studied polymer nanocomposite loaded with layered double hydroxide (LDH) as sorbents for oxyanions such as arsenate, chromate, and vanadate. Under different experimental conditions, the composite exhibited a high oxy anion sorption.

 

 

Keynote Forum

Karin Larsson

Uppsala University, Sweden

Keynote: Diamond surface modification for biomolecule interactions in the design of medical implants

Time : 10:20-11:05

Conference Series Euro Polymer Chemistry 2018 International Conference Keynote Speaker Karin Larsson photo
Biography:

Karin Larsson is a Professor in Inorganic Chemistry at the Department of Materials Chemistry, Uppsala University, Sweden. She has received her PhD in Chemistry. The research was directed towards investigation of molecular dynamic processes in solid hydrates by using solid state NMR spectroscopy. Her scientific focus is on interpretation, understanding and prediction of the following processes/properties for both solid/gas interfaces, as well as for solid/liquid interfaces; CVD growth, interfacial processes for renewable energy applications and interfacial processes for e.g. bone regeneration (incl. biofunctionalization of surfaces).

Abstract:

A vascular necrosis is a disease of cell death in joints, jaw, and hips due to lack of blood supply induced by burnt, inflammation or trauma, etc. The mainstream for curing these days are arterial infusion by partial drug delivery and the replacement of the whole joints by using artificial materials. The first method can only be applied at an early stage of the disease, and the curing results. So for more severe situations, the medical implants will become the only choice. With the need for an improved stability and biocompatibility of the medical implant materials, diamond has recently become interesting as a promising material. The combination of chemical inertness and biocompatibility makes diamond a good material, for e.g. biological applications. In order to promote localized cell adhesion and vascularization onto the diamond-covered medical implants, the prerequisite for pre-adhesion of growth factors onto the diamond surfaces is of largest interest to study more in detail. It is highly necessary that these investigations are performed on an atomic level. Therefore, theoretical simulations is a necessary complementary tool to aid in the analysis of experimental observations and to make recommendations for corresponding experimental studies. With the purpose to tailor-make the medical implant surface by utilizing diamond’s unique properties, the present study has investigated the interaction between diamond and various biomolecules (BMP2, RGD, heparin, fibronectin, VEGF and angiopoietin). The combined effect of various surface plane and termination type (H, O, OH, and NH2) has been of a special interest to study. Three different groupings where obtained with regard to adhesion strength. And all of these three groups showed different dependencies of the surface termination type. For all of these different scenarios, strong bond formations were observed. Evaluation of the methods used showed that the calculated trends in adhesion energy are highly reliable. 

Keynote Forum

Dongmei Cui

Changchun Institute of Applied Chemistry-CAS, China

Keynote: Sequence precisely controlled co-polymerization by using rare-earth metal catalysts
Conference Series Euro Polymer Chemistry 2018 International Conference Keynote Speaker Dongmei Cui photo
Biography:

Dongmei Cui has completed her PhD from Changchun Institute of Applied Chemistry, Chinese Academy of Sciences and Post-doctoral studies from Riken, Japan. She is the Full Professor and Holder of a “Hundred Talent Scientists Program” of Chinese Academy of Sciences, and a Group Leader of Rare-Earth Organometallic Chemistry and Catalysis. She has published more than 180 papers in reputed journals and claimed more than 40 patents.
 

Abstract:

The sequence precisely controlled polymerization of dienes and styrene by using rare-earth metal catalysts will be reported. The polymerization of styrene with extremely high syndioselectivity and catalytic activity have been achieved by using with almost the whole period of rare-earth metals-based catalysts. The DFT simulation reveals that the ligand contributes to lower the LUMO energy of the active species, thus the activation energy is reduced and the catalytic activity increases. Based on this, by changing the central metal size, the random, block, gradient and taper microstructured butadiene-styrene copolymers were obtained. The electron donating side arm of the ligand, on the other hand, may increase the electron density of the active species, therefore, increase its durability to the polar monomers such as, methoxyl and methysilyl styrene’s, leading to, for the first time, highly active and syndioselectivity polymerization of these polar styrene’s to give functional polystyrenes. In addition, the copolymerization of ethylene and styrene with polar styrene are achieved. The position of the substituted polar group influences the coordination mode of the polar styrene to the active metal center and further the reaction ratios of the polar and nonpolar styrene’s, to afford different alternating ethylene/polar-styrene copolymers and styrene-polar styrene copolymers with different monomer sequence distributions. 

  • Supramolecular Polymers|Functional Polymer and its Applications|Recent Developments in Polymer Synthesis

Session Introduction

Eri Yoshida

Toyohashi University of Technology, Japan

Title: Worm-like Vesicles Prepared by Photo Nitroxide-Mediated Controlled/Living Radical Polymerization-Induced Self-Assembly

Time : 12:05-12:40

Speaker
Biography:

Eri Yoshida has completed her Ph.D. in polymer engineering from Tokyo Institute of Technology.  She joined Kyoto Institute of Technology as an assistant professor.  She was also a visiting scientist at the University of North Carolina at Chapel Hill.  She is an associate professor at Toyohashi University of Technology.  She has published more than 100 papers in international journals and has 24 patents.  She has been serving as an editorial board member of some international journals.

 

Abstract:

Worm-like organisms are often observed as baculiform cells and tubular organelles.Worm-like vesicles are regarded as artificial models of biomembrane for these cells and organisms and are expected as new carriers for drug and gene delivery.  This paper describes the synthesis of worm-like vesicles consisting of amphiphilic poly(methacrylic acid)-block-poly(methyl methacrylate-random-methacrylic acid), PMA-b-P(MMA-r-MA), through the photo nitroxide-mediated controlled/living radical polymerization (photo NMP)-induced self-assembly.  The mechanism of the formation and stimuli-responsive behavior of the worm-like vesicles are also described.  The worm-like vesicles were prepared by the photo NMP-induced self-assembly of PMA-b-P(MMA-r-MA) using 4-methoxy-2,2,6,6-tetramethylpiperidine-1-oxyl in an aqueous methanol solution.  It was found that the polymerization had the living nature based on the linear correlation between the molecular weight and monomer conversion.  The copolymer during the early stage of the polymerization produced cup-like vesicles with the thin and flexible bilayer including some holes in the surface.  As the hydrophobic P(MMA-r-MA) block chain was extended by the polymerization progress, the cup-like vesicles were transformed into spherical vesicles, followed by worm-like vesicles due to the incorporation of the spherical vesicles.  The worm-like vesicles had the major axis of 3.41 mm and minor axis of 0.437 mm on average.  The vesicles were sensitive to temperature and transformed into spherical or shorter worm-like vesicles and finally into a fused plane by a temperature increase.  The worm-like vesicles were restored by decreasing the temperature through branched tubules.The worm-like vesicles were also sensitive to pH and salt concentration and more stable than spherical vesicles consisting of PMA-b-P(MMA-r-MA).

 

Oomen P Oommen

Tampere University of Technology, Finland

Title: Designing smart extracellular matrix mimetic hydrogels for tissue engineering

Time : 12:40-13:15

Speaker
Biography:

Oommen P Oommen has received his PhD in Organic Chemistry from Indian Institute of Technology, Bombay. He then moved to Uppsala University, Sweden to pursue his Post-Doctoral studies. In 2016, he joined Tampere University of Technology, Finland as an Assistant Professor where he leads a multidisciplinary team of chemists, molecular biologists and material scientists. His research interests are in the fields of designing functional polymers and biomaterials for tissue engineering, drug delivery and nucleic acid therapeutics. He authored several peer reviewed articles and book chapters. He has also filed several patents and is a Co-founder of a spin-off called ‘Uppsala Therapeutics AB’.
 

Abstract:

Designing injectable gels that mimic the natural extracellular matrix (ECM) has been of great interest in the field of regenerative medicine. We have previously demonstrated that hyaluronic acid (HA) hydrogel having hydrazone crosslinkages could be used for efficient delivery of recombinant human bone morphogenetic protein-2 (rhBMP-2) and form bone in vivo within 6 weeks when injected below the rat periostium. Though rhBMP-2 is very potent for inducing bone formation, recently, extensive debate has taken place on the clinical use of rhBMP-2 since several complications in patients has been observed. This is mainly due to supraphysiological dose that is clinically used since the collagen-based BMP-2 carrier is inefficient and does not stabilize rhBMP-2 in vivo. We have devised a new strategy to engineer hydrazone crosslinked HA hydrogel such that it differentially interacts with rhBMP-2 and provide different release kinetics of the bioactive protein. In order to understand the binding affinity between HA modification and the heterodimer structure of rhBMP-2, we performed computational analysis by performing molecular docking followed molecular dynamics experiments. The results of the computational analysis clearly indicated that electrostatic and Vander Waal’s interactions play a predominant role in stabilizing rhBMP-2 and control its release. To further understand the significance of protein release on bone formation, we performed in vivo bone induction experiments in a rat ectopic model. The in vitro release experiments corroborated very well with the in vivo experiments, which clearly indicate that improving BMP-2 interactions with HA has major impact in stem cell recruitment and bone induction in vivo. Such a biomaterial design strategy could also be easily adapted to deliver other growth factors for different biomedical applications.
 

Sanboh Lee

National Tsing Hua University, Taiwan

Title: Methanol-Induced Crack Healing in Poly(Methyl Methacrylate)/Graphene Nanocomposite

Time : 14:15-14:50

Speaker
Biography:

Dr. Sanboh Lee has been endowed Tsing Hua Chair Professor in the Department of Materials Science and Engineering, National Tsing Hua University. His previous affiliation was Xerox Company. He was a visiting professor at Lehigh University and National Institute of Standards and Technology. To name several of those awards, he was the recipient of 1998 Roon Foundation Award from Federation Society of Coating Technology. He served as an award committee member, TMS. He awarded Fellows of ASM in 2004 and MRS-Taiwan in 2009.  He published 250 articles in peer-reviewed journals.

 

Abstract:

Graphene has remarkable properties; it and its derivatives have been extensively used in many fields such as electronic devices, solar cells and polymeric composites, etc. In this study, we used the solution mixing to produce poly(methyl methacrylate) (PMMA)/graphene powders, and then used the hot press machine to make the specimens of different sizes for different tests. Harmon’s model was considered the anomalous transport, which consists of Case Ι transport and Case II transport. The methanol absorption in PMMA/graphene nanocomposites was found to fit well by using the Harmon’s model. Both energy barriers of Cases Ι and II transport increase with increasing the weight fraction of graphene in nanocomposite, respectively. The cracked specimens were immersed in the methanol at constant temperature. The crack receded from its tip with constant speed at a given temperature. The crack closure speed follows the modified Arrhenius plot and its activation energy is equal to that of Case Ι transport, implying that the crack healing is controlled by Case Ι transport. This implies that the graphene assists to resist the healing progress. The fracture stress of healed PMMA/graphene nanocomposite increases with the weight fraction of graphene in the range from 0 wt.% to 0.5 wt.% and then decreases. The fracture stress of healed specimens increases with the healing time until they reach a plateau and healing temperature. FTIR and Raman spectroscopies were used to analyze chemical bond of PMMA/graphene nanocomposite. Intrinsic viscosity and DSC were also studied to explain the crack healing mechanism.
 

Speaker
Biography:

Jaroslav Minar completed his master studies at the age of 25 years from University of Chemistry and Technology, Prague, where he continues in his doctoral studies under supervision of Professor Jiří Brožek. His fields of interests are polymer nanocomposites based on graphene oxide. He works for an industrial research company, where he focuses on a pyrolysis of a plastic waste.

 

Abstract:

Presence of nanofillers in a polymer matrix can significantly improve properties of resultant nanocomposites. To achieve such improvement, a homogenous dispersion of nanofiller in matrix and strong interfacial adhesion between them are prerequisites. In this presentation, I want to introduce our approaches to enhance these parameters for in situ intercalative polymerization of ε-caprolactam/graphene oxide dispersion to yield polyamide-based nanocomposites. In first procedure, an improvement was achieved by addition of ε-caprolactone to mentioned dispersion followed by anionically initiated polymerization. As a result of improved dispersibility, tensile modulus increased with higher nanofiller concentration. The second procedure consisted in utilization of graphene oxide functionalized by poly(ε-caprolactone). Functionalization was carried out by polymerization of ε-caprolactone initiated by graphene oxide functional groups that resulted in partial covalent attachment of poly(ε-caprolactone) chains to graphene oxide. Polyamide 6 nanocomposites containing functionalized graphene oxide showed higher dynamic modulus and higher exfoliation level than nanocomposites with an initial graphene oxide. As presence of ε-caprolactone/poly(ε-caprolactone) proved to be effective for achieving better dispersibility and interfacial adhesion, I also want to outline one-pot method for covalent functionalization of graphene oxide. This method consists in ε-caprolactone polymerization in dimethylformamide/graphene oxide dispersion directly followed by Steglich esterification to introduce covalent bonds between poly(ε-caprolactone) and graphene oxide.
 

Krishnasamy Balaji

PSG Institute of Technology and Applied Research, India

Title: Investigation on dual effects of photosensitive liquid crystalline polyester

Time : 15:25-16:00

Speaker
Biography:

Dr. K. Balaji, has completed his PhD at the age of 29 years from Ann University. He is working as a Assistant Professor in PSG Institute of Technology and Applied Research, Coimbatore, India. He has published 8 papers in reputed journals and has been serving as an editorial board member of reputed internationl journals. Attended various international conference in USA, Germany, Japan, etc.,

Abstract:

Main chain liquid crystalline polymers with photosensitive groups have attained special attention owing to the presence of dual functionalities. The mesogenic groups contribute to the LC properties and the photoactive groups in the polymer backbone, may facilitates various photochemical reactions in the polymer chains under the influence of UV irradiation. Polymers containing α, β-unsaturated carbonyl groups such as cinnomoyl, benzylidene groups are well studied for their phototransformation phenomena, occurring upon irradiation under UV light and named as negative type photoresists. The photosensitivity of these materials is based on the π-electron density of the chromophores present in the polymer backbone. A series of polyesters containing a photosensitive benzylidene chromophores in the main chain were synthesized from 2,6-bis(4-hydroxybenzylidene) cyclohexanone (BHBCH) with various aliphatic and aromatic diacid chlorides by interfacial polycondensation technique. The molecular structure of the monomer and polymers was confirmed by spectral analyses. These polymers were studied for their thermal stability and photochemical properties. Thermal properties were evaluated by thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC). It was found that the polymers were stable up to 238°C and start degrading thereafter. Increase in acid methylene spacer length decreases the thermal stability. The selfextinguishing property of the synthesized polymers was studied by calculating the limiting oxygen index (LOI) value using Van Krevelen equation. The influence of the length of methylene spacer on phase transition was investigated using DSC and found that isotropic temperature decreases on increasing the acid methylene spacer length. Hot-stage optical polarizing microscopic (HOPM) study showed that polymers P1-P3 exhibit grainy texture in the temperature range of 115-127°C. The photolysis of liquid crystalline polyesters revealed that α, β-unsaturated ketone moiety in the main chain dimerizes through 2π+2π cycloaddition reaction to form a cyclobutane derivative that leads to crosslinking.
 

Tao Tang

Changchun Institute of Applied Chemistry-CAS, China

Title: Synthesis and melt behavior of comb-like (co)polymers with high branching degree

Time : 16:50-17:25

Speaker
Biography:

Tao Tang has completed his PhD in 1991 from Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences. He is a full professor of polymer chemistry in CIAC. He has published more than 230 papers in reputed journals.    
 

 

Abstract:

Using a co-polymer of styrene (St) with 4-(vinylphenyl)-1-butene (VSt) (PSVS) as the backbone, a series of model comb-like polymers were synthesized by means of “graft onto” strategy in this work. The branching density of these comb-like co-polymers is higher than that of traditional graft co-polymer with low branching density, but lower than that of poly(macromolecular monomer). The influences of branching parameters (branching chain length and branching density) and branching chain composition on the rheological properties of comb-like polymers were studied. When the branching chain was polystyrene (PS) chain, which is miscible with the backbone in the PSVS-g-PS, the linear rheological studies showed that PSVS-g-PS presented hierarchical relaxation process, that is, the relaxation of the side chain (intermediate angular frequency region) and the whole comb polymer (the terminal region). When the branching chain was polyethylene (PE) chain, which is immiscible with the backbone in the PSVS-g-PE, in this case, the microstructure and linear rheological properties of the melt strongly depended on the branching density and the length of the side chains in PSVS-g-PE. We further discussed possible reason about the strong effect of branching parameters and branching chain composition on the rheological properties of comb-like polymers.
 

Hanying Zhao

Nankai University, China

Title: Fabrication of Polymer-Protein Hybrids

Time : 16:15-16:50

Speaker
Biography:

Hanying Zhao is a professor in the College of Chemistry, Nankai University. He received his Ph. D. in Macromolecular Chemistry and Physics from Changchun Institute of Applied Chemistry, Chinese Academy of Sciences in 1997 with Prof. Baotong Huang, and carried out post-doctoral researches at Fudan University, Institute of Polymer Research Dresden, University of Florida and Clarkson University. His research interests are in the synthesis and self-assembly of polymers with different topological structures, polymer brushes, polymer-protein hybrids and polymer nanocomposites.

 

 

Abstract:

In recent years, fabrications of polymer-protein hybrids with multiresponsiveness have been attracting increasing attention. In our group, we designed triple-responsive polymer-protein networks based on molecular recognition. Reduced bovine serum albumin (BSA) was modified with multiple β-cyclodextrin (βCD) by thiol-disulfide exchange reaction. The βCDmodified BSA was added into the aqueous solution of acrylamide copolymer with pendant adamantyl group, resulting in the formation of triple-responsive polymer-protein network structures. We also synthesized virus-mimicking protein nanogels with temperature-induced reversible structures and redox responsiveness by crosslinking a thermally responsive polymer poly(di-ethylene glycol) methyl ether methacrylate-co-2-(2-pyridyldisulfide)ethyl methacrylate) with reduced BSA molecules through thiol-disulfide exchange reaction. The lower critical solution temperature (LCST) and sizes of the nanogels can be controlled by controlling the reaction conditions. Co-assembly of positively charged patchy micelles and negatively charged BSA molecules into hybrid vesicles was also investigated. The patchy micelles, which were synthesized using block copolymer brushes as templates, leads to co-assembly with protein molecules into vesicular structures. The average size of the assembled structures can be controlled by the molar ratio of BSA to patchy micelles.